Ipamorelin | CAS 170851-70-4

Product Details

CasNo： 170851-70-4

Molecular Formula： C38H49N9O5

Appearance： White to off-white powder / lyophilized powder

Delivery Time： Confirmed according to quantity, specification, and project requirements

Packing： According to quantity and project requirements

Throughput： Project-based

Purity： ≥98%

Product Overview

Ipamorelin, CAS 170851-70-4, also known by the development code NNC 26-0161, is a synthetic pentapeptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2.

Unlike conventional short peptides composed mainly of natural L-amino acids, Ipamorelin contains several structurally distinctive residues, including Aib, D-2-Nal, and D-Phe, together with a C-terminal amide. These features make its exact sequence and modification profile important for peptide identity and analytical characterization.

Ipamorelin is primarily used in research involving the ghrelin receptor / growth hormone secretagogue receptor (GHSR), peptide–receptor interactions, receptor pharmacology, and non-natural amino-acid peptide studies.

Shandong Juntai Pharmaceutical supports B2B research projects involving Ipamorelin, GHSR-related peptides, and customized short peptides containing non-natural amino acids.

Product Information

 

Product Features

Structurally Distinct Synthetic Pentapeptide

Ipamorelin consists of only five residues, but its sequence contains several non-standard structural elements:

• Aib — α-aminoisobutyric acid
• D-2-Nal — D-2-naphthylalanine
• D-Phe — D-phenylalanine
• Lys-NH2 — C-terminal amidated lysine

This combination differentiates Ipamorelin from conventional short peptides composed entirely of natural L-amino acids.

Defined D-Amino-Acid and Terminal Modification Profile

The presence of D-2-Nal, D-Phe, and a C-terminal amide forms an important part of the molecular identity of Ipamorelin.

For procurement and analytical projects, product verification should therefore consider not only the product name, but also:

• Peptide sequence
• Molecular weight
• D-amino-acid configuration
• C-terminal amidation
• HPLC profile
• MS / LC-MS identity

Clear Relevance to GHSR Research

Ipamorelin belongs to the growth hormone secretagogue peptide research field and is commonly studied in relation to the ghrelin receptor / GHSR.

Its research profile is particularly relevant to:

• GHSR receptor studies
• Ghrelin receptor interaction
• Receptor pharmacology
• Peptide–receptor interaction
• Peptide structure–function research

Suitable for Short-Peptide Characterization

Because Ipamorelin contains both non-natural amino acids and stereochemically defined D-residues, analytical characterization can involve multiple parameters rather than HPLC purity alone.

Depending on project requirements, evaluation may include molecular-weight confirmation, MS / LC-MS identity, sequence-related characterization, terminal modification confirmation, and related impurity analysis.

The ≥98% HPLC value shown on this page is a common research-grade reference specification. Actual supply specifications should be confirmed using batch-specific documentation.

Research Applications

Ghrelin Receptor / GHSR Research

Ipamorelin may be used in studies involving GHSR receptor interaction, receptor pharmacology, and related signaling mechanisms.

These studies can be performed using receptor-expression systems, cell-based models, and quantitative assay platforms depending on the experimental design.

Peptide–Receptor Interaction Studies

Its compact and well-defined sequence makes Ipamorelin useful for investigating how stereochemistry, hydrophobic residues, and terminal modifications influence peptide–receptor recognition.

Relevant research areas include:

• Peptide–receptor interaction
• Ligand–receptor recognition
• Receptor pharmacology
• Short-peptide structure–function studies

Non-Natural Amino-Acid Peptide Research

The presence of Aib, D-2-Nal, and D-Phe also makes Ipamorelin relevant to research involving modified peptide structures.

Potential applications include:

• D-amino-acid peptide studies
• Non-natural amino-acid substitution
• Sequence modification research
• Short-peptide analog design
• Structure–activity relationship studies

Analytical and Structural Characterization

Ipamorelin can also support peptide analysis and analytical method development, including:

• HPLC purity analysis
• MS / LC-MS identity confirmation
• Molecular-weight verification
• Sequence-related characterization
• Terminal modification confirmation
• Related impurity analysis

Custom Support

Ipamorelin-related sequences, GHSR-related peptides, and other short peptides containing non-natural amino acids can be evaluated according to the target structure and analytical requirements.

Project discussions may include:

• Ipamorelin-related sequences
• D-amino-acid substitutions
• Aib and other non-natural amino-acid incorporation
• Site-specific amino-acid replacement
• C-terminal amidation
• N-terminal or C-terminal modifications
• Target purity requirements
• HPLC / MS / LC-MS analysis
• Project-specific quantities and packaging

Feasibility is evaluated according to sequence design, modification type, purity target, quantity, and analytical scope.

Frequently Asked Questions

Can batch-specific COA, HPLC, or MS / LC-MS documentation be provided?

Relevant documentation can be reviewed according to the actual supply batch. If your project requires specific HPLC, MS / LC-MS, molecular-weight confirmation, or other analytical data, please include these requirements in your inquiry.

What is the MOQ for Ipamorelin?

MOQ depends on the requested purity, quantity, packaging format, and current project arrangement. Small R&D quantities and larger project requirements can be discussed separately.

Can higher purity or additional analytical specifications be requested?

Yes. Project-specific requirements involving target purity, related impurities, HPLC, MS / LC-MS, or additional analytical criteria can be evaluated before quotation.

Can peptides containing D-amino acids or other non-natural residues be customized?

Yes. Projects involving D-amino acids, Aib, Nal-related residues, and other non-natural amino acids can be evaluated based on the requested sequence, modification sites, and analytical requirements.

How can batch-to-batch consistency be evaluated?

For ongoing projects, batch consistency can be assessed using the target sequence, molecular weight, HPLC profile, MS / LC-MS results, and batch-specific COA documentation.

Can Ipamorelin-related peptide sequences be customized?

Yes. Ipamorelin-related peptides, site-specific substitutions, terminal modifications, and other GHSR-related peptide projects can be reviewed according to the target structure and technical requirements.

For research and development use only.