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Fmoc-L-Lys[C20-OtBu-γ-Glu(OtBu)-AEEA-AEEA]-OH | CAS 2915356-76-0
- cas：2915356-76-0
- Molecular Formula：
- Purity：99%
- Molecular Weight：
This product is for research and development use only.
Product Details;
CasNo： 2915356-76-0
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH Chemical Properties
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Boiling point |
1225.0±65.0 °C (Predicted) |
|
density |
1.121±0.06 g/cm3 (Predicted) |
|
storage temp. |
2-8°C, sealed storage, away from moisture |
|
pka |
3.87±0.21(predicted) |
|
color |
yellowish |
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH Usage And Synthesis
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Description |
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH (also known as the Tirzepatide side chain, CAS 2915356-76-0; purity 99%) is a key modified amino acid building block used to introduce a long-acting fatty acid chain into therapeutic peptides such as Tirzepatide. This compound is used in the synthesis of tirzepatide via coupling reactions, either by solid-phase peptide synthesis (SPPS) or solution-phase methods. The C20 fatty acid side chain, AEEA and Glu are sequentially attached to the lysine residue. |
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Chemical Properties |
colourless/ yellowish liquid |
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Uses |
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH is used as a pharmaceutical intermediate component. It can be used for the synthesis of Tirzepatide, a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes. |
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