What is the 2-(2-(2-Aminoethoxy)ethoxy)acetic acid?

2-(2-(2-Aminoethoxy)ethoxy)acetic acid is , while it's Molecular Formula is C6H13NO4. [2-(2-Aminoethoxy)ethoxy]acetic Acid is used in the development of chemically modified peptide nucleic acid (PNA) as a probe for qualitative and quantitative detection of DNA. It is also used in the preparation and studies of the biological activities of kappa agonist CovX-bodies.

What is the CAS number for 2-(2-(2-Aminoethoxy)ethoxy)acetic acid?

The CAS number of 2-(2-(2-Aminoethoxy)ethoxy)acetic acid is 134978-97-5.

What is 2-(2-(2-Aminoethoxy)ethoxy)acetic acid (134978-97-5) used for?

Amino-PEG2-CH2CO2H is a PEG compound containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.InChI:InChI=1/C6H13NO4/c7-1-2-10-3-4-11-5-6(8)9/h1-5,7H2,(H,8,9)

What is the 2-(2-(2-Aminoethoxy)ethoxy)acetic acid?

2-(2-(2-Aminoethoxy)ethoxy)acetic acid is , while it's Molecular Formula is C6H13NO4. [2-(2-Aminoethoxy)ethoxy]acetic Acid is used in the development of chemically modified peptide nucleic acid (PNA) as a probe for qualitative and quantitative detection of DNA. It is also used in the preparation and studies of the biological activities of kappa agonist CovX-bodies.

What is the CAS number for 2-(2-(2-Aminoethoxy)ethoxy)acetic acid?

The CAS number of 2-(2-(2-Aminoethoxy)ethoxy)acetic acid is 134978-97-5.

What is 2-(2-(2-Aminoethoxy)ethoxy)acetic acid (134978-97-5) used for?

Amino-PEG2-CH2CO2H is a PEG compound containing an amino group with a terminal carboxylic acid. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.InChI:InChI=1/C6H13NO4/c7-1-2-10-3-4-11-5-6(8)9/h1-5,7H2,(H,8,9)

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AEEA | CAS 134978-97-5

cas：134978-97-5
Molecular Formula：C₆H₁₃NO₄
Purity：99%
Molecular Weight：163.174

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Product Details;

CasNo： 134978-97-5

Molecular Formula： C₆H₁₃NO₄

Reputable factory supply AEEA 134978-97-5 in bulk at low price

Molecular Formula:C6H13NO4
Molecular Weight:163.174
Vapor Pressure:5.23E-05mmHg at 25°C
Melting Point:124.0 to 128.0 °C
Refractive Index:1.466
Boiling Point:323.8 °C at 760 mmHg
PKA:3.37±0.10(Predicted)
Flash Point:149.6 °C
PSA：81.78000
Density:1.177 g/cm³
LogP:-0.23680

2-(2-(2-Aminoethoxy)ethoxy)acetic acid(Cas 134978-97-5) Usage

InChI:InChI=1/C6H13NO4/c7-1-2-10-3-4-11-5-6(8)9/h1-5,7H2,(H,8,9)

134978-97-5 Relevant articles

Preparation method of AEEA

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Paragraph 0067-0069, (2021/10/27)

The invention relates to the technical field of chemical synthesis, in particular to a preparation method of AEA. According to the preparation method of AEEA provided by the invention, amino on diglycol amine is protected by chloroacetyl chloride, then ring formation is carried out in the presence of NaH, and AEEA is obtained through hydrolysis. The method has the advantages of reduced reaction steps, low production cost, high product purity and few impurities, and is suitable for industrial large-scale production.

TARGETED BIFUNCTIONAL DEGRADERS

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Page/Page column 189, (2021/04/17)

The present invention provides, in one aspect, bifunctional compounds that can be used to promote or enhance degradation of certain circulating proteins. In another aspect, the present invention provides bifunctional compounds that can be used to promote or enhance degradation of certain autoantibodies. In certain embodiments, treatment or management of a disease and/or disorder requires degradation, removal, or reduction in concentration of the circulating protein or the autoantibody in the subject. Thus, in certain embodiments, administration of a compound of the invention to the subject removes or reduces the circulation concentration of the circulating protein or the autoantibody, thus treating, ameliorating, or preventing the disease and/or disorder. In certain embodiments, the circulating protein is TNF.

Preparation method of [2-[1-(Fmoc-amino)ethoxy]ethoxy]acetic acid

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Paragraph 0065; 0068; 0070, (2019/09/17)

The invention provides a preparation method of [2-[1-(Fmoc-amino)ethoxy]ethoxy]acetic acid. The preparation method comprises steps as follows: amino protection is performed on diglycolamine by use ofphthalic anhydride, an obtained intermediate and halo-acetic acid or halo-acetate are subjected to a reaction, deprotection or deprotection and hydrolysis are performed, a product reacts with a Fmoc-based amino protection reagent, and [2-[1-(Fmoc-amino)ethoxy]ethoxy]acetic acid is obtained. In the preparation method, phthalic anhydride and diglycolamine are taken as initial raw materials, short time is required by an amino protection reaction, an obtained intermediate compound has good stability, can be preserved for a long time and does not react with water, water-soluble impurities (such asthe raw material diglycolamine, a byproduct phthalic acid and the like) can be separated through extraction, so that an amino protection product with high purity is obtained, and the purity and the yield of the target product are also improved.

Synthesis, Biological Evaluation of Fluorescent 23-Hydroxybetulinic Acid Probes, and Their Cellular Localization Studies

Yao, Hong,Wei, Guoxiang,Liu, Yanpeng,Yao, Hequan,Zhu, Zheying,Ye, Wencai,Wu, Xiaoming,Xu, Jinyi,Xu, Shengtao

, p. 1030 - 1034 (2018/10/15)

23-Hydroxybetulinic acid (23-HBA) is a complex lupane triterpenoid, which has attracted increasing attention as an anticancer agent. However, its detailed mechanism of anticancer action remains elusive so far. To reveal its anticancer mode of action, a series of fluorescent 23-HBA derivatives conjugated with coumarin dyes were designed, synthesized, and evaluated for their antiproliferative activities. Subcellular localization and uptake profile studies of representative fluorescent 23-HBA probe 26c were performed in B16F10 cells, and the results suggested that probe 26c was rapidly taken up into B10F10 cells in a dose-dependent manner and mitochondrion was the main site of its accumulation. Further mode of action studies implied that the mitochondrial pathway was involved in 23-HBA-mediated apoptosis. Together, our results provided new clues for revealing the molecular mechanism of natural product 23-HBA for its further development into an antitumor agent.

134978-97-5 Process route

: C₆H₁₁NO₃

: 134978-97-5,139729-28-5
[2-(N-2-amino ethoxy)ethoxy] acetic acid

Conditions

Conditions	Yield
With hydrogenchloride; In water; for 2h; Reflux;	92%

: 166108-70-9
[2-(2-dibenzylaminoethoxy)ethoxy]acetic acid

: 134978-97-5,139729-28-5
[2-(N-2-amino ethoxy)ethoxy] acetic acid