324017-21-2

  • Product Name:Fmoc-D-Phe(4-NH2)-OH
  • Molecular Formula:C24H22N2O4
  • Purity:99%
  • Molecular Weight:402.44200
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Product Details;

CasNo: 324017-21-2

Molecular Formula: C24H22N2O4

Purity 99% Min Fmoc-D-Phe(4-NH2)-OH 324017-21-2 Spot Supply with Safe Transportation

  • Molecular Formula:C24H22N2O4
  • Molecular Weight:402.44200
  • Boiling Point:671.5±55.0 °C(Predicted) 
  • PKA:3.63±0.10(Predicted) 
  • PSA:101.65000 
  • Density:1.316±0.06 g/cm3(Predicted) 
  • LogP:4.77530 

324017-21-2 Relevant articles

Synthesis of new tetrazolyl derivatives of L- and D-phenylalanine

Tolstyakov,Tolstobrova,Zarubina,Popova,Protas,Chuprun,Trifonov

, p. 1681 - 1685 (2017/01/28)

New tetrazolyl derivatives of L- and D-p...

Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites

Geurink, Paul P.,Van Der Linden, Wouter A.,Mirabella, Anne C.,Gallastegui, Nerea,De Bruin, Gerjan,Blom, Annet E. M.,Voges, Mathias J.,Mock, Elliot D.,Florea, Bogdan I.,Van Der Marel, Gijs A.,Driessen, Christoph,Van Der Stelt, Mario,Groll, Michael,Overkleeft, Herman S.,Kisselev, Alexei F.

supporting information, p. 1262 - 1275 (2013/03/29)

Proteasomes degrade the majority of prot...

N-alkanoylphenylalanine derivatives

-

, (2008/06/13)

Compounds of the formula: are disclosed ...

N-aroylphenylalanine derivative VCAM-1 inhibitors

-

, (2008/06/13)

Compounds of the formula: are disclosed ...

324017-21-2 Process route

N-α-FMOC-4-nitro-L-phenylalanine
95753-55-2,177966-63-1

N-α-FMOC-4-nitro-L-phenylalanine

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
95753-56-3,324017-21-2

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine

Conditions
Conditions Yield
With hydrogen; palladium on activated charcoal; In ethanol; for 1h;
93%
With hydrogen; palladium on activated charcoal; In 1,4-dioxane; for 1h; Ambient temperature;
90%
With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr;
With palladium 10% on activated carbon; ammonium formate; In methanol; at 20 ℃; for 14h;
Multi-step reaction with 2 steps
1: hydrogenchloride; zinc / water; isopropyl alcohol
2: hydrogenchloride; water / 6 h / Reflux
With hydrogenchloride; water; zinc; In water; isopropyl alcohol;
N-α-FMOC-4-nitro-L-phenylalanine
95753-55-2,177966-63-1

N-α-FMOC-4-nitro-L-phenylalanine

isopropyl ether of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-amino-L-phenylalanine

isopropyl ether of N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-amino-L-phenylalanine

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
95753-56-3,324017-21-2

4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine

Conditions
Conditions Yield
With hydrogenchloride; zinc; In water; isopropyl alcohol;

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324017-21-2 Downstream products

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