2216712-66-0
- Product Name：Elexacaftor
- Molecular Formula：
- Purity：99%
- Molecular Weight：597.662
Product Details;
CasNo： 2216712-66-0
Cost-effective customized wholesale Elexacaftor 2216712-66-0
- Molecular Formula:C26H34F3N7O4S
- Molecular Weight:597.662
- Melting Point:206 - 208°C
- Density:1.38±0.1 g/cm3(Predicted)
2216712-66-0 Relevant articles
PROCESSES FOR MAKING MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR
-
Paragraph 0559; 0584-0585; 0588-0589, (2021/08/13)
The disclosure provides processes for pr...
METHODS OF TREATMENT FOR CYSTIC FIBROSIS
-
Paragraph 00208; 00210-00211; 00218, (2020/12/11)
This application describes methods of tr...
METHODS OF TREATMENT FOR CYSTIC FIBROSIS
-
, (2019/02/06)
Compound I of the formula (I) and/or pha...
PHARMACEUTICAL COMPOSITIONS FOR TREATING CYSTIC FIBROSIS
-
, (2019/08/20)
A pharmaceutical composition comprising ...
2216712-66-0 Process route
-
-
(4S)-2,2,4-trimethylpyrrolidine hydrochloride salt
-
![2-chloro-N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethyl-propoxy)pyrazol-1-yl]pyridine-3-carboxamide](/upload/2026/7/64dfbb49-cba7-4c98-8307-e35d0bcad0eb.png)
-
2-chloro-N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethyl-propoxy)pyrazol-1-yl]pyridine-3-carboxamide
-
![N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide](/upload/2026/7/ad4c9934-8ccf-4081-a6fa-4426920fa753.png)
-
2216712-66-0
N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
monoethylene glycol diethyl ether;
at 120 ℃;
for 16h;
Solvent;
Temperature;
Large scale;
|
90% |
|
With
potassium carbonate;
In
monoethylene glycol diethyl ether; dimethyl sulfoxide;
at 120 ℃;
Temperature;
Solvent;
|
90% |
|
With
potassium carbonate;
In
monoethylene glycol diethyl ether; dimethyl sulfoxide;
at 120 ℃;
for 16h;
Solvent;
Temperature;
|
90% |
|
With
potassium carbonate;
In
monoethylene glycol diethyl ether; dimethyl sulfoxide;
at 120 ℃;
Temperature;
Solvent;
|
90% |
|
With
potassium carbonate;
In
1,2-dimethoxyethane; dimethyl sulfoxide;
at 120 ℃;
for 16h;
Solvent;
Temperature;
|
90% |
-
-
(4R)-2,2,4-trimethylpyrrolidine hydrochloride salt
-
-
2-chloro-N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethyl-propoxy)pyrazol-1-yl]pyridine-3-carboxamide
-
![N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4R)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide](/upload/2026/7/bc15b48f-37a9-47c4-b135-cc77e8a0dd6e.png)
-
2216712-66-0
N-(1,3-dimethylpyrazol-4-yl)sulfonyl-6-[3-(3,3,3-trifluoro-2,2-dimethylpropoxy)pyrazol-1-yl]-2-[(4R)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamide
| Conditions | Yield |
|---|---|
|
With
potassium carbonate;
In
1-methyl-pyrrolidin-2-one; monoethylene glycol diethyl ether;
at 130 ℃;
for 40h;
|
61% |
2216712-66-0 Upstream products
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-
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3,3,3-trifluoro-2,2-dimethylpropanoic acid
-
1013647-75-0
2,6-dichloropyridine-3-carboxylic acid tert-butyl ester
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