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Boc-L-His(trt)-Aib-OH | CAS 2061897-68-3
- cas：2061897-68-3
- Molecular Formula：
- Purity：99%
- Molecular Weight：
This product is for research and development use only.
Product Details;
CasNo： 2061897-68-3
Boc-His(Trt)-Aib-OH Chemical Properties
|
Boiling point |
789.3±60.0 °C(Predicted) |
|
density |
1.17±0.1 g/cm3(Predicted) |
|
storage temp. |
Store at room temperature |
|
solubility |
Chloroform (Slightly), DMSO (Slightly) |
|
form |
Solid |
|
pka |
3.43±0.10(Predicted) |
|
color |
White to Off-White |
|
InChIKey |
POZCMPSLNOUKQN-NPFCIKOQNA-N |
|
SMILES |
C(C1C=CC=CC=1)(C1C=CC=CC=1)(C1C=CC=CC=1)N1C=NC(C[C@H](NC(=O)OC(C)(C)C)C(=O)NC(C)(C)C(=O)O)=C1 |&1:24,r| |
Boc-His(Trt)-Aib-OH Usage And Synthesis
|
Purity |
99% |
|
Uses |
Boc-His(Trt)-Aib-OH is a peptide that can be synthesized from Boc-His(Trt)-OH (32926-43-5). |
|
Biosynthesis |
Boc-His(Trt)-Aib-OH is a peptide that can be synthesized from Boc-His(Trt)-OH. |
|
General Description |
Boc-His(Trt)-Aib-OH is a pharmaceutical intermediate used in the preparation of the GLP-1 analogue semaglutide. |
|
Synthesis |
4.3 g of Boc-L-His(Trt)-Aib-OBzl were dissolved in 30 ml THF and 3 ml of ethyl acetate. 0.43 g of the hydrogenation catalyst Pd/C (5%) was added and the compound was hydrogenated at 30° C for 2 h at atmospheric hydrogen pressure using a balloon. The catalyst is filtered oil and washed with 30 ml of ethyl acetate. The solution was stirred for several hours until precipitation occurred. The precipitate is filtered off and dried under vacuum to obtain 2.45 g of Boc-His(Trt)-Aib-OH. |
Relevant Products
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Fmoc-Gln(trt)-Aib-Ala-OHCAS：N/A
-
Fmoc-Lys(Pal-Glu-OtBu)-OHCAS：1491158-62-3
-
L-4,5-dihydroorotic acidCAS：5988-19-2
-
Boc-L-His(Boc)-Aib-OHCAS：2765344-17-8
