Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH
  • Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH

Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH | CAS 252554-79-3

  • cas:252554-79-3
  • Molecular Formula:C25H28 N2 O6
  • Purity:99%
  • Molecular Weight:452.507
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Product Details;

CasNo: 252554-79-3

Molecular Formula: C25H28 N2 O6

Factory Sells Best Quality Fmoc-Ala-Thr[Psi(Me,Me)Pro]-OH 252554-79-3 with USP

  • Molecular Formula:C25H28N2O6
  • Molecular Weight:452.507
  • Boiling Point:681.2±55.0 °C(Predicted) 
  • PKA:3.15±0.60(Predicted) 
  • PSA:105.17000 
  • Density:1.259±0.06 g/cm3(Predicted) 
  • LogP:3.67900 

252554-79-3Relevant academic research and scientific papers

Pseudo-Prolines in Peptide Synthesis: Direct Insertion of Serine and Threonine Derived Oxazolidines in Dipeptides

Woehr, Torsten,Mutter, Manfred

, p. 3847 - 3848 (1995)

Dipeptides containing serine and threonine derived oxazolidines are prepared by reacting side chain unprotected dipeptides containing C-terminal Thr or Ser with dimethoxypropane.The resulting building blocks can be coupled in Fmoc-based solid phase peptide synthesis enhancing peptide solvation by its secondary structure disrupting potential.The present procedure may be considered as a first step towards a reversible modification of structural and functional properties of bioactive peptides and proteins.

Solid phase synthesis of ω-aspartic thioacid containing peptides

Joseph, Ryan,Morales Padilla, Moises,Garner, Philip

supporting information, p. 4302 - 4304 (2015/06/22)

The Fmoc-based solid phase synthesis of unprotected ω-aspartic thioacid containing peptides is demonstrated. The method involves the novel use of a silyl ester as a carboxylate surrogate for mild peptide bond formation in the presence of a reactive ω-aspa

252554-79-3 Process route

C<sub>32</sub>H<sub>34</sub>N<sub>2</sub>O<sub>6</sub>

C32H34N2O6

Fmoc-Ala-Thr(Ψ<sup>Me,Me</sup>pro)-OH
252554-79-3

Fmoc-Ala-Thr(ΨMe,Mepro)-OH

Conditions
Conditions Yield
With palladium 10% on activated carbon; hydrogen; In methanol; for 2h;
77%
Fmoc-Ala-Thr(ox)-OAll

Fmoc-Ala-Thr(ox)-OAll

Fmoc-Ala-Thr(Ψ<sup>Me,Me</sup>pro)-OH
252554-79-3

Fmoc-Ala-Thr(ΨMe,Mepro)-OH

Conditions
Conditions Yield
 
 

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