Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH | CAS 878797-09-2
- cas:878797-09-2
- Molecular Formula:C34H38N2O7
- Purity:99%
- Molecular Weight:586.67500
This product is for research and development use only.
Product Details;
CasNo: 878797-09-2
Molecular Formula: C34H38N2O7
Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH Chemical Properties
|
Boiling point |
795.6±60.0 °C(Predicted) |
|
density |
1.238±0.06 g/cm3(Predicted) |
|
storage temp. |
Store at +2°C to +8°C. |
|
form |
powder |
|
pka |
3.09±0.40(Predicted) |
|
Major Application |
peptide synthesis |
|
InChIKey |
DNJYPUYQFPFOKS-VMPREFPWSA-N |
|
SMILES |
O1C[C@@H](C(O)=O)N(C(=O)[C@@H](NC(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CC2=CC=C(OC(C)(C)C)C=C2)C1(C)C |
Safety Information
|
WGK Germany |
WGK 2 |
|
HS Code |
2934999090 |
|
Storage Class |
11 - Combustible Solids |
Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH Usage And Synthesis
|
Chemical Properties |
White to off-white powder |
|
Uses |
Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH is mainly used in peptide synthesis. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-damaging proline-like TFA-labile oxazolidine. The reason for introducing the pseudoproline residue as a dipeptide is that it avoids the acylation of the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in a single step. The serine residue is regenerated in the normal trans fatty acid mediated cleavage reaction. |
|
reaction suitability |
reaction type: Fmoc solid-phase peptide synthesis |
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-
Fmoc-Gly-Ser[Psi(Me,Me)Pro]-OH
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-
Fmoc-Ser(tBu)-Ser[Psi(Me,Me)Pro]-OH
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![Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH](/upload/2026/7/42-2.jpg)


