Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH
  • Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH
  • Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH

Fmoc-Tyr(tBu)-Ser[Psi(Me,Me)Pro]-OH | CAS 878797-09-2

  • cas:878797-09-2
  • Molecular Formula:C34H38N2O7
  • Purity:99%
  • Molecular Weight:586.67500
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This product is for research and development use only.

Product Details;

CasNo: 878797-09-2

Molecular Formula: C34H38N2O7

Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH Chemical Properties

Boiling point 

795.6±60.0 °C(Predicted)

density 

1.238±0.06 g/cm3(Predicted)

storage temp. 

Store at +2°C to +8°C.

form 

powder

pka

3.09±0.40(Predicted)

Major Application

peptide synthesis

InChIKey

DNJYPUYQFPFOKS-VMPREFPWSA-N

SMILES

O1C[C@@H](C(O)=O)N(C(=O)[C@@H](NC(OCC2C3=C(C=CC=C3)C3=C2C=CC=C3)=O)CC2=CC=C(OC(C)(C)C)C=C2)C1(C)C

Safety Information

WGK Germany 

WGK 2

HS Code 

2934999090

Storage Class

11 - Combustible Solids

Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH Usage And Synthesis

Chemical Properties

White to off-white powder

Uses

Fmoc-Tyr(tBu)-Ser(Psi(Me,Me)pro)-OH is mainly used in peptide synthesis. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-damaging proline-like TFA-labile oxazolidine. The reason for introducing the pseudoproline residue as a dipeptide is that it avoids the acylation of the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in a single step. The serine residue is regenerated in the normal trans fatty acid mediated cleavage reaction.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

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