312624-65-0

  • Product Name:Fmoc-α-Me-Leu-OH
  • Molecular Formula:C22H25 N O4
  • Purity:99%
  • Molecular Weight:367.445
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Product Details;

CasNo: 312624-65-0

Molecular Formula: C22H25 N O4

Fmoc-α-Me-Leu-OH 312624-65-0 with purity >99% Low price in stock

  • Molecular Formula:C22H25NO4
  • Molecular Weight:367.445
  • Vapor Pressure:0mmHg at 25°C 
  • Refractive Index:1.578 
  • Boiling Point:562.652°C at 760 mmHg 
  • PKA:3.95±0.41(Predicted) 
  • Flash Point:294.082°C 
  • PSA:75.63000 
  • Density:1.19g/cm3 
  • LogP:4.80540 

FMOC-ALPHA-ME-LEU-OH(Cas 312624-65-0) Usage

InChI:InChI=1/C22H25NO4/c1-14(2)12-22(3,20(24)25)23-21(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,14,19H,12-13H2,1-3H3,(H,23,26)(H,24,25)/t22-/m0/s1

312624-65-0 Relevant articles

Synthetic Modification within the rPRL Region of Apelin Peptides: Impact on Cardiovascular Activity and Stability to Neprilysin and Plasma Degradation

McKinnie, Shaun M. K.,Wang, Wang,Fischer, Conrad,McDonald, Tyler,Kalin, Kevin R.,Iturrioz, Xavier,Llorens-Cortes, Catherine,Oudit, Gavin Y.,Vederas, John C.

, p. 6408 - 6427 (2017)

Apelin is an important mammalian peptide...

Synthetic method of (2S)-2-N-fluorene methoxycarbonyl amino-2,4-dimethyl valerate

-

Paragraph 0010; 0011; 0012, (2019/03/08)

The invention relates to a synthetic met...

312624-65-0 Process route

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

(S)-2-amino-2,4-dimethylpentanoic acid
105743-53-1

(S)-2-amino-2,4-dimethylpentanoic acid

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,4-dimethylpentanoic acid
312624-65-0

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,4-dimethylpentanoic acid

Conditions
Conditions Yield
With sodium hydroxide; In water; acetone; at 30 ℃; for 12h; pH=9.5; pH-value; Large scale;
60%
C<sub>32</sub>H<sub>35</sub>N<sub>3</sub>NiO<sub>3</sub>

C32H35N3NiO3

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,4-dimethylpentanoic acid
312624-65-0

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2,4-dimethylpentanoic acid

Conditions
Conditions Yield
C32H35N3NiO3; With hydrogenchloride; In methanol; at 70 ℃; for 0.75h;
With sodium carbonate; In water; at 20 ℃; for 0.5h;
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; In water; acetone; at 0 - 20 ℃; for 22h;
95%

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    (S)-2-amino-2,4-dimethylpentanoic acid

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    865468-88-8

    C22H23NO4

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