KTcos® S-Grade Pro-Xylane Wins China Good Ingredients Award

2025.01.02

December 27, 2024 — Shandong Juntai Pharmaceutical Co., Ltd. received the China Good Ingredients Award for its independently developed KTcos® S-Grade Pro-Xylane at the 2024 Cosmetics Developers Conference and Beauty Product Managers Festival in China.

The recognition highlights Juntai Pharmaceutical's ongoing work in cosmetic ingredient development, synthetic process innovation, and quality control.

As a specialized grade of Hydroxypropyl Tetrahydropyrantriol, KTcos® S-Grade Pro-Xylane reflects the company's efforts to improve the manufacturing process and consistency of this widely used cosmetic active ingredient.

Advancing Pro-Xylane Development Through Process Innovation

The China Good Ingredients Award recognizes achievements in cosmetic ingredient innovation, technical development, and industrial application.

Juntai Pharmaceutical's award-winning KTcos® S-Grade Pro-Xylane is the result of continued research into the synthesis and purification of Hydroxypropyl Tetrahydropyrantriol, commonly known in the cosmetics industry as Pro-Xylane.

Since 2019, the company's research team has focused on addressing challenges associated with conventional synthesis methods, particularly impurity control, residual odor, color stability, and stereochemical consistency.

According to the company's previously published technical information, its KTcos® Pro-Xylane development achieved a reported purity of 99.96% and an isomer ratio of 70:30 under specified analytical conditions.

These results reflect the team's research into reaction selectivity, purification methods, and analytical evaluation.

Patented Synthesis Technology Supporting Ingredient Quality

A key aspect of Juntai Pharmaceutical's Pro-Xylane research is the application of asymmetric hydrogenation technology to the manufacturing process.

The development team explored the use of Noyori asymmetric hydrogenation to improve stereochemical control and reduce process-related impurities.

This research contributed to the development of a patented manufacturing method titled:

“A Production Method for Colorless, Odorless, and Borate-Free Pro-Xylane”

Chinese Patent No.: CN202211037235.9

The patented process was developed to address several technical challenges associated with conventional production routes, including the potential presence of borate-related residues and other unwanted impurities.

By refining reaction conditions and purification procedures, the company has worked toward improving ingredient appearance, purity, and manufacturing consistency.

For cosmetic formulators and ingredient developers, these parameters are relevant when evaluating raw materials for use in different formulation systems.

Contributing to Industry Standards for Hydroxypropyl Tetrahydropyrantriol

Beyond manufacturing technology, Juntai Pharmaceutical has participated in efforts to establish more consistent quality evaluation practices for cosmetic raw materials.

In March 2024, the group standard “Cosmetic Ingredient — Hydroxypropyl Tetrahydropyrantriol”, led by Shandong Juntai Pharmaceutical, was officially released.

The standard addresses technical requirements and quality evaluation considerations for Hydroxypropyl Tetrahydropyrantriol used in cosmetic applications.

Its publication represents another step toward improving ingredient specifications and supporting more consistent quality assessment across the industry.

Juntai Pharmaceutical's KTcos® Pro-Xylane technology has also received recognition through other industry awards, including the China Cosmetics Association Innovation Achievement Award and the China General Chamber of Commerce Science and Technology First Prize.

Together, these achievements reflect the company's long-term investment in cosmetic ingredient research, process development, and technical standardization.

Building Long-Term Capabilities in Cosmetic Active Ingredients

Shandong Juntai Pharmaceutical Co., Ltd. specializes in the research, development, and manufacturing of pharmaceutical intermediates and cosmetic raw materials.

The company operates an R&D center in Jinan, Shandong Province, supported by manufacturing facilities and technical teams working across small-molecule synthesis, process optimization, and analytical testing.

Within its cosmetic ingredients portfolio, Juntai Pharmaceutical continues to develop active ingredients for formulation research and industrial applications.

The China Good Ingredients Award marks an important milestone in the development of KTcos® S-Grade Pro-Xylane.

Looking ahead, Juntai Pharmaceutical will continue investing in synthetic process development, quality evaluation, and manufacturing technologies to support the evolving needs of cosmetic ingredient developers and international business partners.

About Shandong Juntai Pharmaceutical

Shandong Juntai Pharmaceutical Co., Ltd. is a China-based manufacturer specializing in pharmaceutical intermediates, cosmetic active ingredients, and custom synthesis services.

With integrated capabilities in chemical research, process development, and manufacturing, the company supports business-to-business customers across the pharmaceutical and personal care industries.

Official Website: https://www.h2opharm.com