AEEA-AEEA (CAS 1143516-05-5): PEG-Based Peptide Building Block and Linker Intermediate for Peptide Synthesis and Bioconjugation
2026.08.11
AEEA-AEEA (CAS 1143516-05-5): PEG-Based Peptide Building Block and Linker Intermediate for Peptide Synthesis and Bioconjugation
Meta Description
AEEA-AEEA (CAS 1143516-05-5) is a PEG-based peptide building block and linker intermediate used in peptide synthesis and bioconjugation research. Shandong Juntai Pharmaceutical supplies high-purity material with comprehensive analytical documentation and custom synthesis support.
Introduction
Peptide synthesis and bioconjugation research often rely on functional building blocks that enable precise molecular spacing, chemical versatility and efficient conjugation strategies. The selection of an appropriate linker structure plays an important role in controlling molecular architecture and optimizing the properties of designed conjugates.
AEEA-AEEA (CAS No. 1143516-05-5) is a PEG-based amino acid derivative used as a peptide building block and linker intermediate in peptide modification, conjugation chemistry and molecular design studies. Its PEG-based framework and reactive functional groups provide researchers with a flexible platform for developing peptide-related conjugates and functional molecules.
Shandong Juntai Pharmaceutical supplies high-purity AEEA-AEEA with analytical documentation and customized synthesis support for global research and development customers.
Chemical Structure and Properties
AEEA-AEEA features a PEG-based spacer framework containing amino and carboxylic acid functionalities, providing reactive sites for further chemical modification.
The PEG segment contributes hydrophilic characteristics and adjustable molecular spacing, while the functional groups support additional derivatization during peptide synthesis and conjugation processes.
Chemical Information
| Item | Specification |
|---|---|
| Product Name | AEEA-AEEA |
| CAS No. | 1143516-05-5 |
| Molecular Formula | C₁₂H₂₄N₂O₇ |
| Molecular Weight | 308.33 g/mol |
| Appearance | White to off-white solid |
| Purity | ≥99% (HPLC) |
| Storage | 2-8°C, protect from light |
Applications in Peptide Synthesis
In peptide chemistry, linker structures are commonly used to control the spatial relationship between functional components and improve the flexibility of molecular design.
PEG-based building blocks such as AEEA-AEEA provide a hydrophilic and flexible spacer element, allowing researchers to construct peptide-related molecules with defined molecular arrangements.
Typical applications include:
- Spacer introduction between peptide-related components
- Conjugation of peptides with small molecules or functional groups
- Development of modified peptide structures and molecular scaffolds
The defined PEG framework provides consistent spacing characteristics, which can be valuable when molecular geometry and structural flexibility are important factors in peptide design.
Role in Bioconjugation Research
Bioconjugation involves the covalent attachment of biomolecules with synthetic molecules or functional components. The linker structure is an important design element because it affects molecular orientation, flexibility and compatibility during the conjugation process.
PEG-based linkers are widely investigated in bioconjugation research due to their flexible architecture and hydrophilic properties.
With its PEG framework and reactive functional groups, AEEA-AEEA can serve as a linker intermediate for applications such as:
- Peptide-small molecule conjugates
- Peptide-based molecular probes
- Functional biomolecule modification
- Customized conjugation strategies
Functional Modification and Coupling Strategies
The amino and carboxylic acid groups within AEEA-AEEA provide opportunities for further chemical transformation during linker synthesis and molecular optimization.
These functional groups support various modification approaches, including:
- Amide bond formation through coupling reactions
- Selective protection and deprotection strategies
- Extension with additional functional components
This chemical versatility makes AEEA-AEEA a useful intermediate for researchers developing customized linker structures and peptide-related molecules.
Quality and Supply Support
Shandong Juntai Pharmaceutical provides AEEA-AEEA (CAS 1143516-05-5) with:
- High-purity material supply (≥99% by HPLC)
- Complete COA documentation
- HPLC and MS analytical data support
- Flexible packaging options according to customer requirements
- Customized synthesis and scale-up capabilities
With expertise in pharmaceutical intermediates, peptide-related building blocks and custom synthesis, Shandong Juntai Pharmaceutical supports global customers with reliable chemical supply solutions and technical documentation.
Related Products and Services
- PEG-based linker intermediates
- Peptide synthesis building blocks
- Custom synthesis services for complex intermediates
